Cheers to 30 years! Activate & earn 5,000 pts PER DAY on $50+ thru 4/22* >

Shop by pet

Jumpstart prevention for fleas & ticks

A dog getting spot-on protection

Dog flea & tick

A cat getting spot-on protection

Cat flea & tick

Flea & Tick

(63 results)
K9 Advantix® II Extra Large Dog Once-A-Month Topical Flea & Tick Treatment for Dogs Over 25 kg
3 sizes

K9 Advantix® II Extra Large Dog Once-A-Month Topical Flea & Tick Treatment for Dogs Over 25 kg

(27)
$65.99 - $161.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
K9 Praventa 360 Topical Flea & Tick Treatment for Dogs - Large Dog - 11-25 kg
2 sizes

K9 Praventa 360 Topical Flea & Tick Treatment for Dogs - Large Dog - 11-25 kg

(18)
$56.99 - $109.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
VECTRA 3D Flea and Tick Treatment for Dogs and Puppies - X Large Dog - 25.1-43 kg

VECTRA 3D Flea and Tick Treatment for Dogs and Puppies - X Large Dog - 25.1-43 kg

(1)
$38.99
$77.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
ZODIAC Infestop PLUS Topical Dogs Over 25 kg

ZODIAC Infestop PLUS Topical Dogs Over 25 kg

(2)
$46.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
K9 Advantix® II Medium Dog Once-A-Month Topical Flea & Tick Treatment for Dogs 4.6 to 11 kg
3 sizes

K9 Advantix® II Medium Dog Once-A-Month Topical Flea & Tick Treatment for Dogs 4.6 to 11 kg

(21)
$59.99 - $142.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Advantage® II Large Cat Once-A-Month Topical Flea Treatment - Over 4 kg
3 sizes

Advantage® II Large Cat Once-A-Month Topical Flea Treatment - Over 4 kg

(108)
$46.99 - $112.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Tickless Ultrasonic Flea & Tick Repeller

Tickless Ultrasonic Flea & Tick Repeller

(122)
$49.99
Enjoy Free Same-day delivery!
Enjoy Free Shipping On Orders $49+.
K9 Advantix® II Large Dog Once-A-Month Topical Flea & Tick Treatment for Dogs 11 to 25 kg
3 sizes

K9 Advantix® II Large Dog Once-A-Month Topical Flea & Tick Treatment for Dogs 11 to 25 kg

(24)
$65.99 - $161.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
K9 Advantix® II Small Dog Once-A-Month Topical Flea & Tick Treatment for Dogs Under 4.5 kg
3 sizes

K9 Advantix® II Small Dog Once-A-Month Topical Flea & Tick Treatment for Dogs Under 4.5 kg

(12)
$59.99 - $142.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Advantage® II Small Cat Once-A-Month Topical Flea Treatment for Cats 2.3 to 4 kg
3 sizes

Advantage® II Small Cat Once-A-Month Topical Flea Treatment for Cats 2.3 to 4 kg

(28)
$46.99 - $112.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Top Paw® Flea Pet Comb

Top Paw® Flea Pet Comb

(103)
$3.99
Enjoy Free Same-day delivery!
Enjoy Free Shipping On Orders $49+.
Atlantick Flea & Tick Natural Repellent Spray
2 sizes

Atlantick Flea & Tick Natural Repellent Spray

(6)
$12.99 - $34.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Parapet Praventa for Cats- Topical Flea Treatment - Large Cats
2 sizes

Parapet Praventa for Cats- Topical Flea Treatment - Large Cats

(4)
$49.99 - $89.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Tickless Home Chemical-free Ultrasonic Flea & Tick Repeller

Tickless Home Chemical-free Ultrasonic Flea & Tick Repeller

(0)
$89.99
Enjoy Free Same-day delivery!
Enjoy Free Shipping On Orders $49+.
Tickless Ecopet Chemical-free Flea & Tick Repeller

Tickless Ecopet Chemical-free Flea & Tick Repeller

(6)
$54.99
Enjoy Free Same-day delivery!
Enjoy Free Shipping On Orders $49+.
Tickless Mini Chemical-free Flea & Tick Repeller - Under 15 kg

Tickless Mini Chemical-free Flea & Tick Repeller - Under 15 kg

(2)
$79.99
Enjoy Free Same-day delivery!
Enjoy Free Shipping On Orders $49+.
Zodiac Infestop II Flea Topical Solution for Cats Over 4 kg - 4 Count

Zodiac Infestop II Flea Topical Solution for Cats Over 4 kg - 4 Count

(2)
$40.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
K9 Praventa 360 Topical Flea & Tick Treatment for Dogs - X Large Dog - over 25 kg
2 sizes

K9 Praventa 360 Topical Flea & Tick Treatment for Dogs - X Large Dog - over 25 kg

(1)
$59.99 - $114.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
K9 Praventa 360 Topical Flea & Tick Treatment for Dogs - Medium Dog - 4.6-11 kg
2 sizes

K9 Praventa 360 Topical Flea & Tick Treatment for Dogs - Medium Dog - 4.6-11 kg

(0)
$54.99 - $104.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Advantage® II Extra Large Dog Once-A-Month Topical Flea Treatment - Over 25 kg
3 sizes

Advantage® II Extra Large Dog Once-A-Month Topical Flea Treatment - Over 25 kg

(8)
$51.99 - $127.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Top Paw® Flea Pet Comb

Top Paw® Flea Pet Comb

(52)
$12.99
Enjoy Free Same-day delivery!
Enjoy Free Shipping On Orders $49+.
Advantage® II Medium Dog Once-A-Month Topical Flea Treatment - 4.6 to 11 kg
3 sizes

Advantage® II Medium Dog Once-A-Month Topical Flea Treatment - 4.6 to 11 kg

(16)
$46.99 - $112.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Capstar™ Small Dog & Cat Oral Flea Treatment - 6 Count

Capstar™ Small Dog & Cat Oral Flea Treatment - 6 Count

(30)
$50.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Capstar™ Large Dog Oral Flea Treatment - 6 Count

Capstar™ Large Dog Oral Flea Treatment - 6 Count

(6)
$54.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
HomeoPet® Host No More Treatment

HomeoPet® Host No More Treatment

(12)
$20.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
ZODIAC® Premise Flea and Tick Home Spray

ZODIAC® Premise Flea and Tick Home Spray

(28)
$35.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
TropiClean Pet Shield Cat Flea & Tick Spray, 473ml

TropiClean Pet Shield Cat Flea & Tick Spray, 473ml

(0)
$19.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Shipping On Orders $49+.
Tick Twister Tick Removal Tool, 3-Pack

Tick Twister Tick Removal Tool, 3-Pack

(0)
$9.99
Enjoy Free Same-day delivery!
Enjoy Free Shipping On Orders $49+.
TropiClean Pet Shield Dog & Home Spray, 473ml

TropiClean Pet Shield Dog & Home Spray, 473ml

(0)
$19.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
TropiClean Pet Shield Max Strength Dog Shampoo, 591ml

TropiClean Pet Shield Max Strength Dog Shampoo, 591ml

(0)
$19.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
VECTRA 3D Flea and Tick Treatment for Dogs and Puppies - Small Dog - 2-4.5 kg

VECTRA 3D Flea and Tick Treatment for Dogs and Puppies - Small Dog - 2-4.5 kg

(0)
$34.99
$69.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
VECTRA 3D Flea and Tick Treatment for Dogs and Puppies - Medium Dog - 4.6-9 kg

VECTRA 3D Flea and Tick Treatment for Dogs and Puppies - Medium Dog - 4.6-9 kg

(1)
$35.99
$71.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
VECTRA 3D Flea and Tick Treatment for Dogs and Puppies - Large Dog - 9.1-25 kg

VECTRA 3D Flea and Tick Treatment for Dogs and Puppies - Large Dog - 9.1-25 kg

(2)
$37.99
$75.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Parapet Praventa for Cats - Topical Flea Treatment - Small Cats
2 sizes

Parapet Praventa for Cats - Topical Flea Treatment - Small Cats

(0)
$49.99 - $89.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
ZODIAC Infestop PLUS Topical Dogs 4.6-11 kg

ZODIAC Infestop PLUS Topical Dogs 4.6-11 kg

(0)
$44.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
ZODIAC Infestop Plus Topical Flea Treatment for Dogs 11-25 kg - 4 Count

ZODIAC Infestop Plus Topical Flea Treatment for Dogs 11-25 kg - 4 Count

(4)
$45.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
ZODIAC Infestop Plus Topical Flea Treatment for Dogs UNDER 4.5 kg - 4 Count

ZODIAC Infestop Plus Topical Flea Treatment for Dogs UNDER 4.5 kg - 4 Count

(0)
$42.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Tickless Tickless EcoHuman Flea & Tick Repeller

Tickless Tickless EcoHuman Flea & Tick Repeller

(1)
$64.99
Enjoy Free Same-day delivery!
Enjoy Free Shipping On Orders $49+.
Zodiac Infestop II Flea Topical Solution for Dogs Over 25 kg - 4 Count

Zodiac Infestop II Flea Topical Solution for Dogs Over 25 kg - 4 Count

(0)
$37.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
Zodiac Infestop II Flea Topical Solution for Dogs 4.6-11 kg - 4 Count

Zodiac Infestop II Flea Topical Solution for Dogs 4.6-11 kg - 4 Count

(2)
$41.99
Get 35% OFF your 1st Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first order by 4/16
Enjoy Free Same-day delivery!
+ 1 more
  2. 1
  3. 2
Download on the App StoreDownload on the Google Play Store
Copyright © 2026 PetSmart LLC
RecallsTerms of Use Privacy Policy Interest-Based Ads Canada Modern Slavery Act
*See Promotional Terms Page for details. Exclusions may apply. While supplies last. Prices & selection may vary by store & online.